Publications

Select Publications:

• Jacob S, Kosaka Y, Bhatlekar S, Denorme F, Benzon H, Moody A, Moody V, Tugolukova EA, Hull G, Kishimoto N, Manne BK, Guo L, Souvenir R, Seliger BJ, Eustes AS, Hoerger K, Tolley ND, Fatahian AN, Boudina S, Christiani DC, Wei Y, Ju C, Campbell RA, Rondina MT, Abel ED, Bray PF, Weyrich AS, Rowley JW. Mitofusin-2 Regulates Platelet Mitochondria and Function. Circ Res. 2024 Jan 19;134(2):143-161.

• Grichine A, Jacob S, Eckly A, Villaret J, Joubert C, Appaix F, Pezet M, Ribba AS, Denarier E, Mazzega J, Rinckel JY, Lafanechère L, Elena-Herrmann B, Rowley JW, Sadoul K. The fate of mitochondria during platelet activation. Blood Adv. 2023 Oct 24;7(20):6290-6302. doi: 10.1182/bloodadvances.2023010423. PubMed PMID: 37624769.

• Kosaka Y, Jacob S, Montenont E, Rowley J. Homology Directed Repair Edited Megakaryocytes For Rapid Screening of Platelet Gene Variant Functions. OC 69.3 (oral presentation), International Society of Thrombosis and Hemostasis (ISTH), July, 2022.

• Montenont E, Bhatlekar S, Jacob S, Kosaka Y, Manne BK, Lee O, Parra-Izquierdo I, Tugolukova E, Tolley ND, Rondina MT, Bray PF, Rowley JW. CRISPR-edited megakaryocytes for rapid screening of platelet gene functions. Blood Adv. 2021 May 11;5(9):2362-2374. doi: 10.1182/bloodadvances.2020004112. PubMed PMID: 33944898; PubMed Central PMCID: PMC8114553.

• Rondina MT, Voora D, Simon LM, Schwertz H, Harper JF, Lee O, Bhatlekar SC, Li Q, Eustes AS, Montenont E, Campbell RA, Tolley ND, Kosaka Y, Weyrich AS, Bray PF, Rowley JW. Longitudinal RNA-Seq Analysis of the Repeatability of Gene Expression and Splicing in Human Platelets Identifies a Platelet SELP Splice QTL. Circ Res. 2020 Feb 14;126(4):501-516. doi: 10.1161/CIRCRESAHA.119.315215. Epub 2019 Dec 19. PubMed PMID: 31852401; PubMed Central PMCID: PMC7323475.

• Rowley JW, Weyrich AS, Bray PF. The Platelet Transcriptome in Health and Disease. Platelets (Fourth Edition), Book Chapter, 2019.

• Rowley JW, Chappaz S, Corduan A, Chong MM, Campbell R, Khoury A, Manne BK, Wurtzel JG, Michael JV, Goldfinger LE, Mumaw MM, Nieman MT, Kile BT, Provost P, Weyrich AS. Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets. Blood. 2016 Apr 7;127(14):1743-51. doi: 10.1182/blood-2015-07-661371. Epub 2016 Jan 14. PubMed PMID: 26773046; PubMed Central PMCID: PMC4825412.

• Noetzli L, Lo RW, Lee-Sherick AB, Callaghan M, Noris P, Savoia A, Rajpurkar M, Jones K, Gowan K, Balduini C, Pecci A, Gnan C, De Rocco D, Doubek M, Li L, Lu L, Leung R, Landolt-Marticorena C, Hunger S, Heller P, Gutierrez-Hartmann A, Xiayuan L, Pluthero FG, Rowley JW, Weyrich AS, Kahr WHA, Porter CC, Di Paola J. Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia. Nat Genet. 2015 May;47(5):535-538. doi: 10.1038/ng.3253. Epub 2015 Mar 25. PubMed PMID: 25807284; PubMed Central PMCID: PMC4631613.

• Rowley JW, Oler AJ, Tolley ND, Hunter BN, Low EN, Nix DA, Yost CC, Zimmerman GA, Weyrich AS. Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes. Blood. 2011 Oct 6;118(14):e101-11. doi: 10.1182/blood-2011-03-339705. Epub 2011 May 19. PubMed PMID: 21596849; PubMed Central PMCID: PMC3193274.

• Kahr WH, Hinckley J, Li L, Schwertz H, Christensen H, Rowley JW, Pluthero FG, Urban D, Fabbro S, Nixon B, Gadzinski R, Storck M, Wang K, Ryu GY, Jobe SM, Schutte BC, Moseley J, Loughran NB, Parkinson J, Weyrich AS, Di Paola J. Mutations in NBEAL2, encoding a BEACH protein, cause gray platelet syndrome. Nat Genet. 2011 Jul 17;43(8):738-40. doi: 10.1038/ng.884. PubMed PMID: 21765413; PubMed Central PMCID: PMC6050511.